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1.
Asian Journal of Andrology ; (6): 73-75, 2003.
Article in English | WPRIM | ID: wpr-300907

ABSTRACT

<p><b>AIM</b>To manage male infertility with obstructive azoospermia by means of percutaneous epididymal sperm aspiration (PESA) and intrauterine insemination (IUI).</p><p><b>METHODS</b>Ninety azoospermic patients with congenital bilateral absence of the vas deferens (BAVD, n=58) or bilateral caudal epididymal obstruction (BCEO, n=32) requesting for fine needle aspiration (FNA), PESA and IUI were recruited. The obstruction was diagnosed by vasography and determination of the fructose, carnitine and alpha-glucosidase levels in the seminal fluid.</p><p><b>RESULTS</b>The mean sperm motility, density, abnormal sperm and total sperm count of the caput epdidymis were 16 %+/-22 %, (12+/-31) x 10(6)/mL, 55 %+/-36 % and (16+/-14) x 10(6), respectively. In the 90 couples, a total of 74 PESA procedures and 66 cycles of IUI were performed. Three pregnancies resulted, including one twin pregnancy giving birth to two healthy boys, one single pregnancy with a healthy girl and another single pregnancy aborted at week 6 of conception. The pregnancy rate per IUI cycle was 4.5 %.</p><p><b>CONCLUSION</b>The birth of normal, healthy infants by IUI using PESA indicates that the caput epididymal sperm possess fertilization capacity. The PESA-IUI programme is a practical and economical procedure for the management of patients with obstructive azoospermia.</p>


Subject(s)
Adult , Female , Humans , Male , Pregnancy , Biopsy, Needle , Epididymis , Cell Biology , Insemination, Artificial , Methods , Oligospermia , Therapeutics , Pregnancy Outcome , Spermatozoa , Cell Biology
2.
National Journal of Andrology ; (12): 353-366, 2002.
Article in Chinese | WPRIM | ID: wpr-287187

ABSTRACT

<p><b>OBJECTIVES</b>The investigation of the testicular volume, the penis length and the T, FSH, LH, PRL levels in serum were taken in 289 adolescent males to provide the valuable data for andrology.</p><p><b>METHODS</b>The adolescent males were grouped according to their age. The testicular volume was measured with testicular model and the T, FSH, LH, PRL levels in serum were determined by immunoenzymetric assay.</p><p><b>RESULTS</b>The male sexual development was rapid from age 11 to 16 and close to that of adult at age 18. Serum PRL of adolescent males was higher than that of adult males.</p><p><b>CONCLUSIONS</b>The age 11 to 16 is a period of rapid growth in sexual maturation. PRL may play an important role in sexual maturation.</p>


Subject(s)
Adolescent , Humans , Male , Body Height , Body Weight , Gonadal Steroid Hormones , Blood , Penis , Physiology , Testis , Physiology
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